The text compiles various studies and references highlighting the importance of medical humanities in shaping the ethical perspectives of medical graduates. It discusses the integration of humanities in medical education, the development of visual diagnostic expertise, and the significance of medical ethics and history in the curriculum. The references underscore the role of humanities in fostering reflective and ethical medical practice.

Interleukin-17 (IL-17) blockers, while beneficial in treating conditions like ankylosing spondylitis and psoriatic arthritis, have paradoxically worsened inflammatory bowel disease (IBD) in patients, leading to the premature termination of various trials. The exact mechanism remains unclear, but potential explanations include interference with the gut mucosal barrier, a regulatory role of IL-17A via IL-24, and excessive inflammation mediated by TL 1A. Understanding this paradox could provide insights into the complex role of IL-17 in autoimmune diseases and chronic inflammation.

Interleukin-17 (IL-17) blockers, while beneficial in treating conditions like ankylosing spondylitis and psoriatic arthritis, have paradoxically worsened inflammatory bowel disease (IBD) in patients, leading to the premature termination of various trials. The exact mechanism remains unclear, but potential explanations include interference with the gut mucosal barrier, a regulatory role of IL-17A via IL-24, and excessive inflammation mediated by TL 1A. Understanding this paradox could provide insights into the complex role of IL-17 in autoimmune diseases and chronic inflammation.

A study involving 630 patients with autoimmune rheumatic diseases (AIRD) who received two doses of SARS-CoV-2 vaccines found that postvaccination antibody titres can predict protection against COVID-19. Patients were categorized into good responders (GR), inadequate responders (IR), and non-responders (NR) based on their antibody levels. Breakthrough infections were highest among NR, followed by IR, and least in GR. Significant predictors of breakthrough infections included antibody response, type of vaccine, and use of mycophenolate mofetil. Multivariate Cox regression analysis showed that NR had a significantly higher risk of breakthrough infections.

US West Coast diesel differentials have significantly declined since the beginning of summer due to the recovery of stocks and refinery utilization post-spring maintenance. California-grade diesel in Los Angeles hit its lowest price since June 20, while West Coast refinery maintenance and utilization data indicate a substantial recovery. The increase in CARB-diesel supply and overall West Coast ULSD stocks has contributed to the price decline, with similar trends observed in San Francisco and Portland.

Union employees at Century Aluminum's Sebree smelter in Kentucky have ratified a new five-year labor agreement. The contract, covering approximately 500 workers, addresses wages and health care. The Sebree smelter, which recently returned to full operation after a power outage, is one of Century's best-performing facilities. Century is also investing $75 million to rebuild potlines at its Hawesville smelter and operates additional smelters in South Carolina and Iceland.

India's elite engineering schools, particularly the Institutes of Technology (IIT), continue to attract a high number of applicants despite the potential impact of US President Donald Trump's 'hire American' policy on H-1B visas. The intense competition for admission, driven by the promise of high salaries and opportunities to work abroad, remains undeterred. However, the pressure to succeed has led to significant stress among students, with some even resorting to suicide. While many graduates do not pursue engineering jobs, opting instead for careers in IT, consulting, and finance, the global demand for their skills remains strong, with countries like Canada stepping in to fill the gap left by the US.

The article discusses the rise of websites in India that allow users to design and customize their own fashion items, such as handbags, T-shirts, and formal wear. ICustomMadeIt.com offers personalized products and a 'custom concierge' service. Jack Of All Threads enables users to design, market, and sell T-shirts and hoodies. Faaya.in specializes in custom suits, shirts, dresses, and traditional Indian attire. 16Stitches provides an online platform for designing custom shirts with a home visit tailor service. TShirtLoot offers T-shirt customization with the option to use 13 Indian languages. The article highlights the entrepreneurial opportunities these platforms provide and includes testimonials from users who have successfully created and sold their designs.

JoinMyWedding.com is a new startup that allows foreign tourists to attend Indian weddings for a fee. The concept was developed by Australian start-up mentor Orsi Parkanyi after realizing there was a market for such a service. The platform was co-founded by Parkanyi, Márti Matécsa, and Pallavi Savant. The website lists a variety of weddings, including traditional Indian weddings and themed weddings like a Lord of the Rings event in Russia. The focus is on India, with weddings listed in several cities and partnerships with travel agents to promote sales. Tickets include accommodation and access to all wedding events, with prices starting at around Rs 20,000. The service is not only for foreigners but also for Indians interested in experiencing weddings from other regions or cultures. Kataria Tours and Travels, a Delhi-based agency, has partnered with JoinMyWedding to offer this unique cultural experience to its clients.

The article discusses the lives of individuals in India who bear a striking resemblance to famous personalities such as Salman Khan, Narendra Modi, Sachin Tendulkar, Baba Ramdev, Shah Rukh Khan, Arvind Kejriwal, and Rajinikanth. These lookalikes have capitalized on their appearances to earn a living by appearing in advertisements, movies, and political campaigns. However, they also face the challenge of establishing their own identities separate from the celebrities they resemble. The article highlights their experiences, the opportunities and pitfalls of their unique situations, and their aspirations beyond being just lookalikes.