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justo ortega is a journalist based in Guaynabo, Puerto Rico
Portfolio
Antiangiogenics in Malignant Granular Cell Tumors: Review of the Literature
Granular cell tumors (GCTs) are an ultra-rare subtype of soft tissue sarcoma with limited survival in metastatic cases. This review highlights the growing evidence for the efficacy of pazopanib in treating advanced GCTs, showing substantial activity in terms of dimensional responses. Pazopanib is suggested as a preferable treatment option for advanced GCTs. The review also discusses the pathology, molecular biology, and other targeted therapies for GCTs, including crizotinib and PI3K inhibitors, while noting the ineffectiveness of dasatinib and megestrol. The study emphasizes the need for further research and global collaboration to improve treatment strategies for this rare disease.
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